What do the snow leopard in the Kangchenjunga Conservation Area in Nepal, flood water diversion on Mount Kenya, waste separation in Manantlán (Mexico), conflict transformation workshops in Sudan, Ethiopia and Egypt, law and policy analysis with vigilantes in the Tunari park in Bolivia, and a radio program for Nepali migrants have in common? They are all so-called Partnership Actions for Mitigating Syndromes of Global Change (PAMS)—projects in an innovative research approach developed by the Swiss National Centre of Competence in Research (NCCR) North–South. This approach merges scientific knowledge and local, tacit or “non-scientific” real-life knowledge in a genuine, grounded research experience.